In this study, the Nylon 6/Modified PET Sheath-Core conjugated fibers were produced by the conjugated melt-spinning machine, then processed by two different ways to obtain the FDY and DTY, so that the rate of alkali-soluble of modified PET in the sheath-core conjugated fibers could be measured with altering the different treatment temperature、time and concentration of NaOH .As the result of experiments, the rate of alkali-soluble of modified PET in the sheath-core conjugated fibers were increased evidently with increasing the treatment temperature and treatment time and concentration of NaOH, it was also demonstrated by the cross-sectional observation of fibers with optical microscope. The processed ways of filament was also an important factor of rate of alkali-soluble of modified PET in the sheath-core conjugated fibers.