重度肥胖者罹患阻塞型睡眠呼吸中止之盛行率及臨床預測因子

The Prevalence and Clinical Predictors of Obstructive Sleep Apnea in Morbidly Obese Patients

廖筱蓁(Hsiao-Chen Liao) ； 林政佑(Cheng-Yu Lin) ； 蔡幸芳(Hsing-Fang Tsai) ； 吳俊良(Jiunn-Liang Wu)

《台灣耳鼻喉頭頸外科雜誌》 48卷3期 (2013/09) Pp. 219-227

https://doi.org/10.6286/2013.48.3.219

摘要

BACKGROUND: Obesity has become more common in current society and it was reported to be related to the occurrence of obstructive sleep apnea (OSA). To our knowledge, the prevalence of OSA in morbidly obese Asians is poorly documented. The aim of our study was to investigate it in the Asian bariatric population. Furthermore, we tried to identify clinical predictors of OSA for bariatric patients.METHODS: This single-center study conducted from January 1, 2011 to December 31, 2012. Eighty one morbid obese subjects preparing for bariatric surgery were enrolled. All participants completed a series of examinations for the diagnosis of OSA before the surgery. Objective assessments included overnight polysomnography (PSG) and the other demographic data. Subjective assessments used questionnaires (Epworth Sleepiness Scale, Snore Outcomes Survey and Pittsburgh Sleep Quality Index).RESULTS: The subjects were 81 obese subjects (34 men and 47 women). The mean body mass index (BMI) was 43.0 kg/m^2 (SD = 7.7). The data of the PSG showed that the average AHI was 26.0 time/hour (SD = 83.2), the average O2 saturation was 94.2% (SD = 3.7), the lowest O2 saturation was 74.7% (SD = 12.8) and the snore index was 253.3 time/hour (SD = 268.1). The overall prevalence of OSA was 86.4% (70/81). The severities of OSA were significant with male predominant and older (p ＜ 0.05).CONCLUSIONS: OSA is highly prevalent in bariatric patients. Sex and age were the predictors of OSA severity.

關鍵字

肥胖 ； 阻塞性睡眠呼吸中止症 ； 盛行率

並列摘要

BACKGROUND: Obesity has become more common in current society and it was reported to be related to the occurrence of obstructive sleep apnea (OSA). To our knowledge, the prevalence of OSA in morbidly obese Asians is poorly documented. The aim of our study was to investigate it in the Asian bariatric population. Furthermore, we tried to identify clinical predictors of OSA for bariatric patients.METHODS: This single-center study conducted from January 1, 2011 to December 31, 2012. Eighty one morbid obese subjects preparing for bariatric surgery were enrolled. All participants completed a series of examinations for the diagnosis of OSA before the surgery. Objective assessments included overnight polysomnography (PSG) and the other demographic data. Subjective assessments used questionnaires (Epworth Sleepiness Scale, Snore Outcomes Survey and Pittsburgh Sleep Quality Index).RESULTS: The subjects were 81 obese subjects (34 men and 47 women). The mean body mass index (BMI) was 43.0 kg/m^2 (SD = 7.7). The data of the PSG showed that the average AHI was 26.0 time/hour (SD = 83.2), the average O2 saturation was 94.2% (SD = 3.7), the lowest O2 saturation was 74.7% (SD = 12.8) and the snore index was 253.3 time/hour (SD = 268.1). The overall prevalence of OSA was 86.4% (70/81). The severities of OSA were significant with male predominant and older (p ＜ 0.05).CONCLUSIONS: OSA is highly prevalent in bariatric patients. Sex and age were the predictors of OSA severity.

並列關鍵字

obesity ； OSA ； prevalence