經內科療法治癒之棘狀阿米巴角膜炎－壹例報告

Acanthamoeba Keratitis Successfully Treated Medically-Report of a Case

李世忠(Shih-Chung Lee) ； 曾順輝(Sung-Huei Tseng)

《中華民國眼科醫學會雜誌》 32卷3期 (1993/09) Pp. 360-363

https://doi.org/10.30048/ACTASOS.199309.0016

摘要

棘狀阿米巴角膜炎(Acanthamoeba Keratitis)為壹罕見之角膜炎，其罹患者多與配戴隱形眼鏡有關。由於早期診斷不易，藥物治療反應不佳，最後多訴諸於治療性角膜移植。本篇報告壹例阿米巴角膜炎患者，經由propamidine, neomycin, polymyxin B點眼藥及Ketoconazole口服治療而痊癒，忠患癒後矯正視力可達1.0。本例經驗顯示早期診斷及適當藥物投于，可治療此頑疾及避免或延緩角膜移植之必要。

並列摘要

Acanthamoeba keratitis, usually associated with contact lens wearing, is a rare but devastating corneal disease. Due to difficulty in early diagnosis and poor response to most antibiotics, therapeutic penetrating keratoplasty is often tried to eradicate the pathogen in uncontrolled disease. Herein, we report a case of early acanthamoeba keratitis successfully treated medically. Following intensive treatment of combined topical propamidine, miconazole, neomycin and polymyxin B, and oral ketoconazole, the corrected visual acuity returned to 20/20 finally. This report showed that with early diagnosis and adequate anti-amebal therapy, eradication of the parasite as well as recovery of visual acuity is possible, which may make the therapeutic or rehabilitative penetrating keratoplasty unnecessary.

並列關鍵字

Acanthamoeba keratitis ； Medical treatment