長期低氧暴露對心肺功能之影響

The Effects of Chronic Hypoxia Exposure on Cardiorespiratory Function

黃奕仁(Yi-Jen Huang)

《體育學報》 28期 (2000/03) Pp. 389-397

https://doi.org/10.6222/pej.0028.200003.4038

摘要

To investigate the effect of chronic hypoxia exposure on cardiorespiratory function, five members of Mt. CHO OYU (8201m) expedition were examined before and after their successful climbing. Following tests were undertaken: (1) anthropometric measurements: body fat weight, lean body mass, circumference and skinfold on each position of body; (2) hemotological measurements: red blood cell (RBC), hemotocrit (Hct%) and hemoglobin (Hb); (3) pulmonary function tests: vital capacity (FVC), FEV1.0%; (4) incremental exercise testing in normoxia (sea level) and hypoxia (FIO2=10.5%, 5700m): maximum oxygen uptake (VO2 max), HRmax, maximum oxygen pulse, ventilation. The results revealed that: (1) body fat weight increased 18.7% (7.82 to 9.28kg, p ＜ 0.05) and LBM decreased 5.6% (p＜0.05); (2) most of all circumference measurements decreased, especially in the low extremity which thigh circumference decreased 7.2% (p＜0.05), calf circumference decreased 3.2% (p＜0.05), the total muscle mass (totle circumferences – totle skinfodes) decreased 3.7% (p＜0.05); (3) RBC increased 21% (4.34 to 5.27 mil/cu mm), Hct%, Hb significantly increased 21.8% (40.88 to 49.78%), 24% (13.98 to 17.34 g/dl) respectively; (4)FVC didn’t change significantly, FEV1.0% increased 8.66% but not significantly. Although VO2max, HRmax, maximun oxygen pulse in normoxia incremental exercise test didn’t change significantly, during hypoxia increased exercise test, VO2max increased 33.1% (19.77 to 26.32 ml/min/kg significantly, oxygen pulse increased 18.6% (6.72 to 7.97 ml/min/beat, p＜0.05), and the maximum ventilation increased 27% (88.2 to 112 L, p＜0.1). The results of this study suggests that the enhencement of VO2max, especially in hypoxia situation, after chronic hypoxia exposure may be caused by peripheral effects of hematological changes and central effects of cardiorespiratory function improvements.

關鍵字

低 ； ,遠征隊 ； 肺功能 ； 心肺功能 ； 紅血球 ； 淨體重

並列摘要

To investigate the effect of chronic hypoxia exposure on cardiorespiratory function, five members of Mt. CHO OYU (8201m) expedition were examined before and after their successful climbing. Following tests were undertaken: (1) anthropometric measurements: body fat weight, lean body mass, circumference and skinfold on each position of body; (2) hemotological measurements: red blood cell (RBC), hemotocrit (Hct%) and hemoglobin (Hb); (3) pulmonary function tests: vital capacity (FVC), FEV1.0%; (4) incremental exercise testing in normoxia (sea level) and hypoxia (FIO2=10.5%, 5700m): maximum oxygen uptake (VO2 max), HRmax, maximum oxygen pulse, ventilation. The results revealed that: (1) body fat weight increased 18.7% (7.82 to 9.28kg, p ＜ 0.05) and LBM decreased 5.6% (p＜0.05); (2) most of all circumference measurements decreased, especially in the low extremity which thigh circumference decreased 7.2% (p＜0.05), calf circumference decreased 3.2% (p＜0.05), the total muscle mass (totle circumferences – totle skinfodes) decreased 3.7% (p＜0.05); (3) RBC increased 21% (4.34 to 5.27 mil/cu mm), Hct%, Hb significantly increased 21.8% (40.88 to 49.78%), 24% (13.98 to 17.34 g/dl) respectively; (4)FVC didn’t change significantly, FEV1.0% increased 8.66% but not significantly. Although VO2max, HRmax, maximun oxygen pulse in normoxia incremental exercise test didn’t change significantly, during hypoxia increased exercise test, VO2max increased 33.1% (19.77 to 26.32 ml/min/kg significantly, oxygen pulse increased 18.6% (6.72 to 7.97 ml/min/beat, p＜0.05), and the maximum ventilation increased 27% (88.2 to 112 L, p＜0.1). The results of this study suggests that the enhencement of VO2max, especially in hypoxia situation, after chronic hypoxia exposure may be caused by peripheral effects of hematological changes and central effects of cardiorespiratory function improvements.

並列關鍵字

Hypoxia ； expedition ； pulmonary function ； cardiorespiratory function ； LBM

參考文獻

Boutellier U.,D, Deriaz,P.E. Di Prampero,P. Cerretelli(1990).Aerobic Performance at Altitude: Effects of Acclimatization and Hematocrit with Reference to Training.J. Sports Med..11

Cerretelli P.(1991).In: Response and Adaptation to Hypoxia.

Mcardle, William D.(1991).Exercise physiology.

Robertson,Robert J.,Ronald Gilcher,Kenneth F. Metz,Gary S. Skrinar,Thomas G. Allison,Henry T. Bahnson,R. Anne Abbott Richard Becker,Jeffery E. Falkel(1982).Effect of induced erythrocythemia on hypoxia tolerance during physical exercise.J. Appl. Physiol: Respirat. Environ. Exercise Physiol.53(2)

Sukhamay Lahiri,Neil S. Chemiack,Robert S. Fitzgerald(1991).Response and Adaptation to Hypoxia.