Searching for different kinds of folks, complementary or alternative therapies by many cancer patients might delay the best timing for treatment and diminished the efficacy of the legitimate medical therapies. Evidence based utilization of complementary therapies in clinical cancer patient care is a great challenge to nurses. This article described the concept of evidence-based practice, the definitions of complementary therapies, the applications of complementary therapy in nursing practice, the research of complementary therapies in cancer care, and the limits along with the prospects of complementary therapies. The clinical nurses are advised to develop the knowledge of complementary therapies, integrate the results of related studies, and apply them to cancer patient care.