Radio Frequency Identification (RFID) has taken center stage at retail and consumer products forum. RFID is not a new technology; it has been in use for many years. In this paper, we first review RFID technology and the components that form the backbone of the RFID system. Next, we demonstrate the usefulness of RFID in supply chain and present some data mining challenges in RFID. Finally a real-life case study is used to illustrate how organizations are using RFID data.