Antioxidant Activities of Different Wild Bitter Gourd (Momordica Charantia L. Var. Abbreviata Seringe) Cultivars

實驗以花蓮區農業改良場提供之臺灣原生16種不同品種山苦瓜（Momordica charantia L. var. abbreviata Seringe，MCA），分別以冷水（水抽物，H）與甲醇（甲醇抽取物，M）抽取，進行抗氧化活性分析。結果發現品種之間清除DPPH自由基與氫氧自由基的活性都不相同，最有效品種之50％有效濃度清除DPPH自由基為181 μg/mL（H）及246 μg/mL（M）；最有效品種之50％有效濃度清除氫氧自由基為148 μg/mL（H）及 7 μg/mL（M）。在抑制銅離子誘導低密度脂蛋白過氧化活性表現，特別是甲醇抽取物（M）在4000 μg/mL濃度下，表現出保護效果（以TBARS表示）幾乎與 0.8 mM Trolox效果相當。以上的結果顯示，山苦瓜抽取物未來也許可以開發為天然抗氧化保健食品。

關鍵字

山苦瓜；抗氧化活性； DPPH自由基；低密度脂蛋白過氧化

並列摘要

Antioxidant activity assays were conducted using water (H) and methanolic (M) extracts of sixteen cultivars from indigenous wild bitter gourd (Momordica charantia L. var. abbreviata Seringe, MCA) in Taiwan. The scavenging activities against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radicals were different among MCA cultivars and the concentrations of 50% scavenging activity (IC50) for the effective cultivar was 181 μg/mL (H) and 246 μg/mL (M) in the former extract and 148 μg/mL (H) and 37 μg/mL (M) in the latter. For inhibitory activities against Cu(superscript 2+)-induced low-density-lipoprotein peroxidation, most MCA cultivars at 4000 μg/mL (especially for M extracts) showed protective activities and were equivalent to 0.8 mM Trolox by thiobarbituric acid reactive substance assays. These useful data may help promote the use and further research of MCA as an antioxidant in the health food industry.

並列關鍵字

Momordica charantia L. var. abbreviata Seringe (MCA) ； Antioxidant activity ； 2,2-diphenyl-1-picrylhydrazyl (DPPH) ； Low-density-lipoprotein peroxidation

國際替代計量

Antioxidant Activities of Different Wild Bitter Gourd (Momordica Charantia L. Var. Abbreviata Seringe) Cultivars

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