Effect of Sedentary Work and Exercise on Lipid and Lipoprotein Metabolism in Middle-aged Male and Female African Workers

J. Ikekpeazu Ebele ； E. Neboh Emeka ； C. Maduka Ignatius ； A. Ufelle Silas ； C. Iyida Chikaodili ； E. Ejezie Fidelis ； G. Anyanwu Emeka

《Asian Journal of Medical Sciences》 1卷3期 (2009/11) Pp. 117-120

並列摘要

Lipids and lipoproteins are essential constituents of the body and their activities assist in maintenance of the body homeostasis. Sedentary lifestyle, as predisposed by sedentary work has been shown to lead to inactivity which could lead to lipid disorders. The present study is therefore designed to ascertain the effect of sedentary work on the lipid status of sedentary workers and to their predisposition to coronary heart disease (CHD). The fasting serum TC, TG, HDL-C, LDL-C and VLDL levels of 80 apparently healthy Nigerian male and female workers, living sedentary lifestyles, aged between 20 and 60 years old were analyzed. Forty agematched non-sedentary subjects were used as control. The mean ± SD for all the groups showed a statistically significant increase (p＜0.05) in TC, TG, LDL-C and VLDL when compared with the control subjects, w hile the HDL-C showed a significant decrease (p＜0.05) when compared with the control. Test of difference in mean ± SD (gender difference) showed a statistically significant increase (p＜0.05) in TG and LDL-C while a non significant increase (p＞0.05) was observed in TC, HDL-C and VLDL of females in comparison to their male counterparts. A statistically significant increase (p＜0.05) was observed in the lipid profile of sedentary workers not undergoing exercise. This study indicates that for both gender, sedentary lifestyle predisposes one to the risk of CHD and lack of exercise worsens the situation. The female participants were more at risk of CHD than the males, based on their lipid profile assessment.

並列關鍵字

Artery ； assessment ； coronary ； gender ； lifestyle ； predispose and test