Meridian and acupuncture are important concept in Chinese traditional medicine. There have been many methods to observe the characteristics in acupoint, for example, electrical resistance or temperature measurement in human skin. In this study we try to extract the microcirculatory property of acupuncture point by laser Doppler flowmetry. We performed three groups of experiment to compare the measurement flux between acupoint and non-acupoint. Which include He-Gu(Li4) and Yang-Xi(Li5) in Group A, He-Gu and San-Jian(Li3) in Group B, and Jing-Gu(B46) and Shu-Gu(B45) in Group C. The results revealed that the average LDF flux signal on acupoint is larger than that on non-acupoint, with p all smaller than 0.05 by paired t-test. If implies that, there may exist a more abundant microcirculatory perfusion on acupoint.