Agricultural biotechnology projects have been assigned as national technology plans by the Execute Yen in 1998. There are seven core biotechnology projects, divided into twenty-nine alternatives, including floricultural and ornamental plants, plant protection, aquaculture, development on animal vaccine, medicinal and health crops production techniques, environmental protection technique, preservative treatment of agricultural products. Within the budgetary limits how to appropriate choose alternatives is important. The paper uses a fuzzy multi-criteria decision making method to select agricultural biotechnology development alternatives based on the concept of technology transfer. The algorithm for selecting alternatives is based on the fuzzy set theory and fuzzy linguistic variables methed. A ranking index based on the decision maker's optimistic (or pessimistic attitude) is proposed to determine the ranking order of all alternatives on experts decision making process.