The purpose of this study was to investigate the cooperative relationship of elite blind marathoners and their running guides, understand their cooperative model, and discover the facors that influence their persistent cooperation. Qualitative research method was adopted in this study, observe and in-depth interview were the main source of information collection. A purposeful sampling was used to select 4 elite blind marathoners who won prizes in several national games and their 7 running guides. The conclusion is: (1) cooperation of blind marathoner and running guide is a process of adjustment. (2) the essential factor of persistent cooperation is enthusiasm for running and emotion of coexistence(cohesion). (3) DEVASTATOR—the force of 1 plus 1 greater than two.