The purpose of this study is to present the pressure and adjustment that children with Asperger syndrome and their families may experience with the school. The results indicate that children with Asperger syndrome experience great pressure on school learning, and also personal relationships with peers and teachers from children's perspectives. From parents' perspectives, parents experience pressures from their children's classmates, teachers, entrance examination issues, bullying, children refusing going to school or school transferring issues. This study intends to provide insights to help to provide friendly leaning school environment for children with Asperger syndrome and to support their families for better improving children's learning and interpersonal relationship.