Title

Factors Associated with Low Bone Mineral Density among Taiwanese Women Receiving Health Check-ups

Translated Titles

體檢婦女低骨質密度的相關因素

DOI

10.29461/TGG.200805.0004

Authors

李燕鳴(Yin-Ming Li)

Key Words

骨質疏鬆症 ; 雙能量X光吸收儀 ; 危險因素 ; dual-energy X-ray absorptiometry ; osteoporosis ; risk factors

PublicationName

台灣老年醫學暨老年學雜誌

Volume or Term/Year and Month of Publication

3卷2期(2008 / 05 / 01)

Page #

106 - 119

Content Language

英文

Chinese Abstract

Objectives: The incidence of osteoporosis has risen with increased life expectancy in recent decades. Osteoporosis-related fractures lead to significant morbidity and mortality and poor functional outcome. The risk of fracture escalates significantly as the bone mineral density (BMD) decreases. We assessed the prevalence of low bone mass in women and its associated factors. Methods: Subjects who had received health check-ups at a teaching hospital in eastern Taiwan were invited to participate in this study. A self-administered questionnaire was used to assess their demographic characteristics, diet, lifestyles, reproductive and medical history. Bone mineral density of the posterior-anterior lumbar spine (L1-L4) was measured by dual energy X-ray absorptiometry. A spinal BMD less than 0.85 g/cm^2 was defined as low BMD(subscript L). Univariate and multiple logistic regression analyses were performed to estimate the association of risk factors. Results: Data on 769 Taiwanese women, aged from 36 to 75 years old, with a mean age of 54.9 years, were included in this study. The mean of BMD(subscript L) significantly decreased after aged 50. The percentage of low BMD(subscript L) was three times higher in postmenopausal women (55.7%) than in their premenopausal counterparts (16.0%). The percentage of osteoporosis (T-score≦-2.5) was about 40% in women from 61~70 years old and 70% in those from 71~75 years old. Among the premenopausal women, three significant factors associated with low BMD(subscript L) were identified: current smoking, low body weight (<49 kg) and an age ≥51 years. For postmenopausal women, vegetarianism and an age≥61 were significant factors associated with low BMD(subscript L). Conclusions: Low BMD(subscript L) is prevalent among pre- and post- menopausal women. Women should be assessed for risk factors of low BMDL and referred for BMD testing as indicated. Quitting smoking and keeping an ideal body weight should be emphasized at consultation. For the vegetarians, adequate nutritional supplements and appropriate bone density evaluation should be provided to avoid the risk of osteoporosis.

English Abstract

Objectives: The incidence of osteoporosis has risen with increased life expectancy in recent decades. Osteoporosis-related fractures lead to significant morbidity and mortality and poor functional outcome. The risk of fracture escalates significantly as the bone mineral density (BMD) decreases. We assessed the prevalence of low bone mass in women and its associated factors. Methods: Subjects who had received health check-ups at a teaching hospital in eastern Taiwan were invited to participate in this study. A self-administered questionnaire was used to assess their demographic characteristics, diet, lifestyles, reproductive and medical history. Bone mineral density of the posterior-anterior lumbar spine (L1-L4) was measured by dual energy X-ray absorptiometry. A spinal BMD less than 0.85 g/cm^2 was defined as low BMD(subscript L). Univariate and multiple logistic regression analyses were performed to estimate the association of risk factors. Results: Data on 769 Taiwanese women, aged from 36 to 75 years old, with a mean age of 54.9 years, were included in this study. The mean of BMD(subscript L) significantly decreased after aged 50. The percentage of low BMD(subscript L) was three times higher in postmenopausal women (55.7%) than in their premenopausal counterparts (16.0%). The percentage of osteoporosis (T-score≦-2.5) was about 40% in women from 61~70 years old and 70% in those from 71~75 years old. Among the premenopausal women, three significant factors associated with low BMD(subscript L) were identified: current smoking, low body weight (<49 kg) and an age ≥51 years. For postmenopausal women, vegetarianism and an age≥61 were significant factors associated with low BMD(subscript L). Conclusions: Low BMD(subscript L) is prevalent among pre- and post- menopausal women. Women should be assessed for risk factors of low BMDL and referred for BMD testing as indicated. Quitting smoking and keeping an ideal body weight should be emphasized at consultation. For the vegetarians, adequate nutritional supplements and appropriate bone density evaluation should be provided to avoid the risk of osteoporosis.

Topic Category 醫藥衛生 > 婦產科與老幼科