Title

六味地黃丸對微循環血流影響之研究

Translated Titles

A study of Liu-Wei-Dihuang Pills effect on microcirculation

Authors

江文睿

Key Words

六味地黃丸 ; 中藥 ; 微循環 ; Liu-Wei-Dihuang ; herb ; microcirculation

PublicationName

元智大學電機工程學系學位論文

Volume or Term/Year and Month of Publication

2008年

Academic Degree Category

碩士

Advisor

許昕

Content Language

繁體中文

Chinese Abstract

中藥的歷史悠久,在藥性和藥理上有許多種分類方法,其中以藏象學說和經絡學說為主要依據的就是歸經理論,而我們的研究就是以經絡和穴道上的微循環來觀察六味地黃丸對人體的影響。   在實驗上我們以雷射都卜勒血流計來觀察微循環,而且依照六味地黃丸的藥效選擇腳上的太谿作為主要的量測位置,另外還選擇太谿旁的非穴道和手上的合谷作為對照,除了服藥的實驗,我們還進行了空白實驗來確保服藥實驗的變化確實是服藥的影響,在實驗結果中我們看到服用六味地黃丸會使太谿的微循環血流量上升,血流量變化比例也較空白實驗來得多,這代表六味地黃丸可能具有改善下半身微循環的功效。

English Abstract

There are many properties for herbs. One of these properties is meridian tropism theory. It is also an important concept in Chinese Medicine Pharmacology. In this study, we try to extract the microcirculatory property of acupoint and meridian to study the effects of taking Liu-Wei-Dihuang.   In the experiment, we use Laser Doppler flowmetry (LDF) to monitor microcirculation. The measurement site are Tai-Xi (Ki3), nonacupoint near Tai-Xi, and He-Gu (Li4). We also do blank test to contrast with the experiment of taking Liu-Wei-Dihuang. The result of this study indicates that Liu-Wei-Dihuang increase the blood flow at Tai-Xi, and make the variation of blood flow at Tai-Xi larger than it is in the blank test. This phenomenon imply that Liu-Wei-Dihuang may improve the microcirculation of lower extremities.

Topic Category 電機通訊學院 > 電機工程學系
工程學 > 電機工程
Reference
  1. [2]Sagar SM, Wong RK, Chinese medicine and biomodulation in cancer patients-Part one. , Current Oncology, 15(1): 42-48, 2008.
    連結:
  2. [8]Wang YY, Chang SL, Wu YE, Hsu TL, Wang WK, Resonance. The missing phenomenon in hemodynamics. , Circulation Research, 69: 246-249, 1991.
    連結:
  3. [10]Wang WK, Hsu TL, Wang YY, Liu-wei-dihuang: a study by pulse analysis. , The American Journal of Chinese Medicine, 26(1): 73-82, 1998.
    連結:
  4. [11]Wang WK, Chen HL, Hsu TL, Wang YY, Alteration of pulse in human subjects by three Chinese herbs. , The American Journal of Chinese Medicine, 22(2): 197-203, 1994.
    連結:
  5. [12]Steinke JM, Shepherd AP, Role of light scattering in whole blood oximetry. , IEEE transactions on bio-medical engineering, 33: 294-301, 1986.
    連結:
  6. [13]Goertz DE, Christopher DA, Yu JL, Kerbel RS, Burns PN, Foster FS, High-frequency color flow imaging of the microcirculation. , Ultrasound in medicine & biology, 26(1): 63-71, 2000.
    連結:
  7. [15]Wu YC, Hsu JH, Liu IM, Liou SS, Su HC, Cheng JT, Increase of insulin sensitivity in diabetic rats received die-huang-wan, a herbal mixture used in Chinese traditional medicine. , Acta pharmacologica Sinica, 23(12): 1181-1187, 2002.
    連結:
  8. [16]Ko??tka A, Legrand-Fernandez MS, Abraham P, Fizanne L, Fromy B, Sigaudo-Roussel D, Saumet JL, Low skin temperature impairs the cutaneous vasodilator response to local progressive pressure strain. , Microvascular research, 67(2): 203-206, 2004.
    連結:
  9. [17]Hsiu H, Chao PT, Chiang WR, Hsu CL, Jan MY, Wang WK, Lin Wang YY, Effect of Pulse Number on the Pulse-Based Synchronized-Averaging Analysis in Laser Doppler Signal, Biomedical Engineering, 19(3): 179-185, 2007.
    連結:
  10. [18]黃世銘, 穴道雷射都卜勒血流量特性之研究, 元智大學, 2007.
    連結:
  11. [19]Chao PT, Jan MY, Hsiu H, Hsu TL, Wang WK, Lin Wang YY, Evaluating microcirculation by pulsatile laser Doppler signal. , Physics in medicine and biology, 51(4): 845-854, 2006.
    連結:
  12. [1]行政院衛生署, 民國95年衛生統計系列(一)死因統計上卷, http://www.doh.gov.tw/statistic/data/衛生統計叢書2/95/上冊/index.htm, 2007.
  13. [3]朱建平、黃健, 醫學史話, 國家出版社, 2003.
  14. [4]魏子孝、聶莉芳, 中醫中藥史, 文津出版社, 1994.
  15. [5]王筠默、姜名瑛, 中藥藥理學, 上海科學技術出版社, 1985.
  16. [6]印會河、張伯訥, 中醫基礎理論, 上海科學技術出版社, 1984.
  17. [7]Wang WK, Lo YY, Hsu TL, Wang Lin YY, Resonance of organs with the heart, Advance in Biomedical Engineering Hemisphere, Washington, D.C., 259-268, 1989.
  18. [9]王唯工, 氣的樂章, 大塊文化出版社, 2002.
  19. [14]Zheng WC, Hu SJ, Fang Q, Intervention of liuwei dihuang pill on lupus nephropathy treated with cylophosphamide and glucocorticoids, Chinese journal of integrated traditional and Western medicine, 25(11): 983-985, 2005.