二氧化鈦奈米顆粒對發育中斑馬魚之行為研究

林純瑤

doi:10.6346/NPUST.2010.00157

3.237.71.247，Hello！

Close
Search Quick Search Advanced Search Publication Search	Personal Service Member Login Searching History Use Bonus Card SYMSKAN
Browse Browse by University of Graduate Thesis Browse by Pinyin of Graduate Thesis Browse by Conference Proceedings Topic Browse by Conference Proceedings Publisher Browse by Pinyin of Conference Proceedings Browse by eBook Category Browse by eBook Topic Browse by eBook Publisher
Customer Services Authorize Airiti Recommend a Journal

Search Symbol (Half-width)	Description of Search Symbols
Space	"AND" indicates the intertwining of key terms used in a search
Double Quotation Marks ("") ( " " )	Double quotation marks indicate the beginning and end of a phrase, and the search will only include terms that appear in the same order of those within the quotations. Example: "image process" ： " image process "
?	Indicates a variable letter. Entering two ? will indicate two variable letters, and so on. Example: "Appl?", search results will yield apple, apply… e , appl y … ( (often used to English word searches) )
*	Indicates an unlimited number of variable letters to follow, from 1~n. Example: Enter "appl*", search results will yield apple, apples, apply, applied, application…(often used in English word searches) e , appl es , appl y , appl ied , appl ication … ( (often used to English word searches) )
AND、OR、NOT	Boolean logic combinations of key words is a skill used to expand or refine search parameters. (1) AND (1) AND: Refines search parameters (2) OR (2) OR: Expands search parameters (3) NOT: Excludes irrelevant parameters

DOI stands for Digital Object Identifier （ D igital O bject I dentifier ） ,
and is the unique identifier for objects on the internet. It can be used to create persistent link and to cite articles.

Using DOI as a persistent link

To create a persistent link, add「http://dx.doi.org/」「 http://dx.doi.org/ 」 before a DOI.
For instance, if the DOI of an article is 10.5297/ser.1201.002 , you can link persistently to the article by entering the following link in your browser: http://dx.doi.org/ 10.5297/ser.1201.002 。
The DOI link will always direct you to the most updated article page no matter how the publisher changes the document's position, avoiding errors when engaging in important research.

Cite a document with DOI

When citing references, you should also cite the DOI if the article has one. If your citation guideline does not include DOIs, you may cite the DOI link.

DOIs allow accurate citations, improve academic contents connections, and allow users to gain better experience across different platforms. Currently, there are more than 70 million DOIs registered for academic contents. If you want to understand more about DOI, please visit airiti DOI Registration （ doi.airiti.com ）。

Data Source

College of Agronomy > Department of Aquaculture
Bio-Agriculture > Fishery

Bibliography Management Tool

Related Links

Report an Issue

Purchase Single Articles

Download PDF

二氧化鈦奈米顆粒對發育中斑馬魚之行為研究

Behavioral effects of titanium dioxide nanoparticles on larval zebrafish (Danio rerio)

林純瑤 , Masters　　Advisor：陳德豪;曾美珍　　

繁體中文 DOI： 10.6346/NPUST.2010.00157

奈米顆粒二氧化鈦；斑馬魚；行為；啶橘染色；氧化緊迫； titanium dioxide nanoparticles (TiO2 NP) ； zebrafish ； behavior ； acridine orange (AO) ； oxidative stress

Abstract │ Reference (82) │ Altmetrics

Abstract 〈TOP〉

Parallel Abstract 〈TOP〉

Titanium dioxide nanoparticles (TiO2 NP) is a novel material that can be used in healthcare, cosmetics and environmental products. However, TiO2 NP would eventually flow into aquatic environment. Increased surface area of nanoparticles can potentially cause damage to aquatic lives. Behavior of fish provides connections to fish biochemistry and physiology processes, and can be a valuable tool to detect the influence of the environmental pressure on fishes. In addition, observing fish behaviors allow us to have a perspective on the influence of pollutants at the population level. In this study, fertilized zebrafish eggs were exposed to TiO2 NP (control, 0.1, 1.5, 1, 5 and 10 mg/l), and the hatching rate, mortality, malformation rate were observed every 12 hours. In addition, larval swimming ability was evaluated at 120 hours post fertilization. The result showed no significant difference in hatchability, survival, and malformation rate between groups, but TiO2 NP at 0.1, 0.5, 1 mg/l caused decreased average velocity and activity level of larval zebrafish. Co-exposure to either the glutathione precursor, N-acetylcysteine (NAC), or the glutathione synthesis inhibitor, buthionine sulfoximine (BSO), did not significantly alter the behavioral effects resulting from TiO2 NPs. Acridine orange staining of larvae showed no significant difference in apoptosis level between groups. Our data suggests that other factor(s) besides oxidative stress may contribute to the behavioral toxicity of TiO2 NPs. Our study also showed that the behavioral endpoints were more sensitive than the others (e.g., hatchability and survival) to detect toxicity of TiO2 NPs on developing fish.

Reference ( 82 ) 〈TOP〉

Atchison, G.J., Henry, M.G., Sandheinrich, M.B., 1987. Effects of metals on fish behavior: a review. Environmental Biology of Fishes 18, 11-25.
連結：
Barakat, M.A., 2005. Adsorption behavior of copper and cyanide ions at TiO2-solution interface. Journal of Colloid and Interface Science 291, 345-352.
連結：
Beauvais, S.L., Jones, S.B., Brewer, S.K., Little, E.E., 2000. Physiological measures of neurotoxicity of diazinon and malathion to larval rainbow trout (Oncorhynchus mykiss) and their correlation with behavioral measures. Environmental Toxicology and Chemistry 19, 1875-1880.
連結：
Bjerselius, R., Lundstedt-Enkel, K., Olse´n, H., Mayer, I., Dimberg, K., 2001. Male goldfish reproductive behavior and physiology are severely affected by exogenous exposure to 17-estradiol. Aquatic Toxicology 53, 139-152.
連結：
Brewer, S.K., Little, E.E., DeLonay, A.J., Beauvais, S.L., Jones, S.B., Ellersieck, M.R., 2001. Behavioral Dysfunctions Correlate to Altered Physiology in Rainbow Trout (Oncorynchus mykiss) Exposed to Cholinesterase-Inhibiting Chemicals. Archives of Environmental Contamination and Toxicology 40, 70-76.
連結：

Altmetrics

〈TOP〉

E-mail ：

When an article is available to download, a notice will be sent to your mailbox address.

E-mail ：