The incidence of cardiac metastases is 9.1% in oncologic patients, and lung cancer is the leading source. Most patients are asymptomatic, and if symptoms exist, they may mimic cardiovascular diseases. Hemodynamic instability is often life-threatening. Here, we report 2 rare cases of fatal cardiac metastases in patients with non-small cell lung cancer with hemodynamic instability. With the advances in clinical treatment and prolonged survival, the incidence of cardiac metastases is increasing. Physicians should be alert that new cardiac symptoms in patients with known malignancy can be caused by cardiac metastases. Although limited, some data shows early detection and multidisciplinary management in selected patients may improve the outcome.