This research takes the rescue transportation of emergency birth of a pregnant woman as an example and tries to construct the operational security knowledge library using the Operating Risk Management and the Topic Maps method to prevent accident during rescue operation. In the view point of emergency rescue organization such as fire prevention department that the Topic Maps is suitable to integrate all kinds of non-structurized information, that disperse in the fire prevent rescue department. The Topic Maps can using the subject for each kind of social stratum or between the non-social stratum-like information subject constructs the elastic knot, and will penetrate the data, that spread in all information resources, which in conformity with the same subject, and them will achieve the construction of security knowledge data base of fire fighting and emergency rescue.