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Intravascular Large B-cell Lymphoma Presenting as Diffuse Pulmonary FDG Uptake on FDG-PET

血管內大型B細胞淋巴瘤於正子電腦斷層造影以肺部瀰散性氟化去氧葡萄糖吸收做表現

摘要


A 45-year-old woman with rheumatic arthritis history suffered from fever and some airway symptoms. She was treated as airway infection and rheumatic arthritis flare up initially. Owing to recurrent fever, she was admitted. Chest computed tomography (CT) showed left lower lung minimal ground-glass opacities and splenomegaly. Pulmonary samples from video-assisted thoracoscopic surgery revealed diffuse large B-cell lymphoma. Because subsequent FDG-PET for staging showed a characteristic diffuse pulmonary FDG uptake pattern without corresponding CT abnormality, intravascular large B-cell lymphoma (IVLBCL) was suspected. Further pathologic review made the final diagnosis of IVLBCL, a subtype of diffuse large B-cell lymphoma.

關鍵字

18F-FDG lung lymphoma PET/CT

並列摘要


一位45歲有類風濕性關節炎病史的婦女出現發燒與呼吸道症狀,起初被以呼吸道感染和類風溼性關節炎加劇做治療,但因反覆性發燒而住院。其胸部電腦斷層顯示細微的毛玻璃狀病灶與脾臟腫大,影像輔助胸腔鏡手術取出的肺部標本經病理診斷為瀰漫性大型B細胞淋巴瘤,為了疾病分期所做的正子電腦斷層造影則因呈現出特徵性的肺部瀰漫性氟化去氧葡萄糖吸收而懷疑病患為血管內大型B細胞淋巴瘤,其後病理再閱的結果認為該病患確屬於瀰漫性大型B細胞淋巴瘤中的此種亞型。

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