- 期刊
林木天然物之抗細菌活性
Antibacterial Activity of Natural Products from Woody Plants
摘要
細菌是存在於日常生活中的微生物之一，由細菌引起最常見的相關疾病為腸胃管道方面的疾病，例如霍亂、痢疾等。抗生素的存在雖然能有效地抑制細菌的活性和生長，然而，大量濫用導致細菌的抗藥性逐年增加，降低了抗生素的功用。近年來，由林木萃取天然物及其活性之研究漸漸受到重視，許多研究結果顯示，抽出成分具有良好的抗細菌活性。本文係介紹細菌種類、致病機制與抗藥機制，以及現今實驗室常用的抗細菌評估方法，並將抽出成分以骨架做一歸類，探討具有抗細菌活性的林木天然物，將相關的文獻做一整體性的整理和討論。期望往後能由林木抽出物中獲得更多具有活性的抽出成分，開發林木天然物在醫療抗菌方面之用途。
並列摘要
Bacterium is one of the familiar microbes in our life. Intestinal and stomach diseases caused by bacteria are the most common illnesses such as cholera and dysentery. Although antibiotics inhibit both activity and growth of bacterium, overuse of antibiotics would lead to antibiotic resistance of bacteria. The incidences of bacteria that resist antibiotics have grown alarmingly, and the efficiency of known antibiotics has decreased. In recent years, there has been a growing interest in studying the natural extracts from woody plants and their bioactivities. Some antibacterial natural products have been found possessing excellent activities. The purpose of this paper is to introduce the types of bacteria, bacterial pathogenesis, antibiotic mechanisms, the evaluation methods, and natural products which possessed antibacterial activity. Exploration of more novel natural products from woody plants as bactericides is emphasized and worthy of further investigations.
延伸閱讀
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