The Fatty Acid Composition of Colostrum in Three Geographic Regions of China

中国三个不同地理区域人初乳脂肪酸构成

Yi-Xiong Gao ； Jian Zhang ； Chun-Rong Wang ； Li-Xiang Li ； Qing-Qing Man ； Peng-Kun Song ； Li-Ping Meng ； Øvyind Lie ； Livar Frøyland

《Asia Pacific Journal of Clinical Nutrition》 22卷2期 (2013/04) Pp. 276-282

https://doi.org/10.6133/apjcn.2013.22.2.02

摘要

目的：描述中国三个不同区域人初乳脂肪酸构成。方法：募集来自于淡水河湖地区、沿海及内陆地区的妊娠晚期孕妇。调查妊娠第34周前一个月的膳食 消费频率。采集产后3至5天内初乳样品。分析初乳中31种脂肪酸的含量。结果：三地区孕妇膳食与食用油消费模式存在显著差异。淡水河湖地区，沿海和内陆地区产妇的初乳总脂含量（均值±标准差，g/100 g初乳）分别为2.17±1.26、2.50±1.39和2.68±1.26（经孕妇年龄校正后p=0.265）。初乳中主要饱和、单不饱和、n-6多不饱和及n-3多不饱和脂肪酸分别为16:0、18:1n9、18:2n6和18:3n3。河湖地区初乳脂肪中总SFA和总n-6PUFA的百分含量最低，而总MUFA和总n-3PUFA的百分含量最高。三地区初乳DHA含量（均值±标准差，%）分别为0.51±0.18、0.52±0.20和0.35±0.13（经孕妇年龄校正后p=0.0002）。妊娠晚期海鱼摄入频率与初乳中DHA构成呈正相关（r=0.203，p=0.040）。结论：中国三个不同地理区域，人初乳脂肪酸构成存在差异，并与母体膳食模式相关。

關鍵字

初乳 ； 脂肪酸 ； 海鱼 ； 菜籽油 ； 二十二碳六烯酸

並列摘要

Purpose: To describe the fatty acid composition of human colostrum in three different regions of China. Methods: Women were recruited from river/lake, coastal and inland regions of China during late pregnancy. Their diet frequency was assessed during the 34th week of pregnancy. Colostrum samples were collected between postpartum days 3 and 5. Thirty-one different fatty acids were separated and identified in colostrum. Results: There were significant differences among the women in the three regions with respect to food and culinary oil consumption patterns. The mean±SD fat content (g/100 g) of colostrum from river/lake, coastal and inland regions was 2.17±1.26, 2.50±1.39 and 2.68±1.26, respectively (p=0.265, adjusted by pregnant women’s age). The main saturated, monounsaturated, n-6 polyunsaturated and n-3 polyunsaturated fatty acids in colostrum were 16:0, 18:1n9, 18:2n6 and 18:3n3, respectively. Colostrum from river/lake region had the lowest composition of total SFA and of total n-6 PUFA and the highest composition of total MUFA and of total n-3 PUFA. The amount of DHA (22:6n3) in colostrum (mean±SD, % wt/wt) was 0.51±0.18, 0.52±0.20 and 0.35±0.13 in the river/lake, coastal and inland regions, respectively (p=0.0002, adjusted by pregnant women's age). Frequency of maternal marine fish intake during the late pregnancy was positively correlated with DHA in colostrum (r=0.203, p=0.040). Conclusions: The fatty acid composition of colostrum differs across geographical regions in China, which may be related to differences in maternal dietary pattern.

並列關鍵字

human colostrums ； fatty acids ； marine fish ； rapeseed oil ； docosahexaenoic acid

參考文獻

Zhang J, Wang Y, Meng L, Wang C, Zhao W, Chen J, Ghebremeskel K, Crawford MA. Maternal and neonatal plasma n-3 and n-6 fatty acids of pregnant women and neo- nates from three regions of China with contrasting dietary patterns. Asia Pac J Clin Nutr. 2009;18:377-88.

Fidler N, Koletzko B. The fatty acid composition of human colostrum. Eur J Nutr. 2000;39:31-7.

Chappell JE, Clandinin MT, Kearney-Volpe C. Trans fatty acids in human milk lipids: influence of maternal diet and weight loss. Am J Clin Nutr. 1985;42:49-56.

Marangoni F, Agostoni C, Lammardo AM, Giovannini M, Galli C, Riva E. Polyunsaturated fatty acid concerntrations in human hindmilk are stable throughout 12-months of lacta- tion and provide a sustained intake to the infant during ex- clusive breastfeeding: an Italian study. Br J Nutr. 2000;84: 103-9.

Agostoni C. Role of long-chain polyunsaturated fatty acids in the first year of life. J Pediatr Gastroenterol Nutr. 2008;47:41-4.