單次攝取不同劑量紅景天對肌肉損傷之影響

目的：本研究旨在比較單次服用不同劑量紅景天對於運動後立即性以及恢復一天後，血液中肌肉損傷指標肌酸激酶（creatine kinase, CK）以及肝損傷指標丙胺酸轉胺酶（alanine aminotransferase, ALT）與麩草醋醯轉氨酶（aspartate aminotransferase, AST）活性之影響，藉以評估何種劑量最具保護效果。方法：受試者為臺北市立大學曲棍球代表隊14名選手。本實驗採雙盲交叉試驗設計（double-blind and cross-over design），受試者在單次服用紅景天和安慰劑後，接受漸增強度模式的跑步機運動至耗竭，並於運動前、運動後立即與運動後24小時採集血液分析肌酸激酶、麩丙酮酸轉氨酶、麩草酸轉氨酶活性。結果：服用紅景天高劑量組之選手，在運動後立即之肌酸激酶明顯低於控制組，並且達顯著差異（p ＜ .05）；服用低、高劑量組紅景天之選手，在運動後24小時肌酸激酶明顯低於控制組，並且達顯著差異（p ＜ .05）；服用紅景天高劑量組之選手，在運動後24小時肌酸激酶明顯低於低劑量組之選手，並且達顯著差異（p ＜ .05）；服用紅景天高劑量組之選手，在運動後24小時肌酸激酶明顯低於運動前測，並且達顯著差異（p ＜ .05）。結論：單次服用紅景天對於選手有助於恢復運動後肌肉損傷之修補，對運動選手之運動損傷恢復有立即之影響，尤以高劑量相較於低劑量攝取能獲致更好的促進效果。

關鍵字

肌酸激酶；麩丙酮酸轉氨酶；麩草酸轉氨酶

並列摘要

Purpose: We investigated the effects of acute doses of ＂Rhodiola rosea＂ on muscle damage markers in hockey players after an exhaustive exercise. Methods: In thisdouble-blind cross-over designed study, 14 hockey players from University of Taipei hockey team were participated. Two different doses of ＂Rhodiola rosea＂ (low: 100 mg; high: 1,000 mg) were given to subjects 1-h prior to participate in exhaustive exercise. Blood samples were collected before ingestion (fasting), immediately after exercise and 24-h after exercise to measure the concentrations of creatine kinase, glutamic pyruvic transaminase and glutamate oxaloacetate transaminase. Results: Acute ingestion of ＂Rhodiola rosea＂ (100 and 1,000 mg) effectively decreasedmuscular damageat 24-h after exercise. We further noticed that the ingestion of high dose was better than the low dose. Furthermore, high was beneficial in the recovery of muscular damage after exercise, and affects the recovery of fatigue immediately.