Pulmonary sarcomatoid carcinoma is a rare form of non-small cell lung cancer that comprises 0.1% to 0.4% of all lung malignancies. Patients are predominantly male smokers with a median age of 60 to 70 years. The clinical course is aggressive and the prognosis is significantly worse than that of other forms of non-small cell lung cancer. Pulmonary sarcomatoid carcinoma usually presents as a large, solitary, peripheral mass with chest wall invasion, and very rarely as a protruding endobronchial tumor with pulmonary vessel invasion. We report the case of a 59-year-old female non-smoker with the unusual presentation of pulmonary sarcomatoid carcinoma (subtype spindle cell carcinoma) as an endobronchial mass obstructing the left main bronchus and invading the left pulmonary artery.