Bronchopulmonary sequestration, also referred to as pulmonary sequestration, is a rare congenital malformation of the lower respiratory tract, in which a mass of non-functioning lung tissue is unable to communicate normally with the tracheobronchial tree. From a clinical standpoint, accurately diagnosing bronchopulmonary sequestration is crucial to the differential diagnosis of malignancies. PET-CT allows accurate differentiation between benign and malignant nodules. However, when bronchopulmonary sequestration is complicated by chronic infection from an organism such as Aspergillus, PET-CT will often detect a high FDG uptake, a symptom which may also indicate malignancy. Thus, choosing CT angiography rather than PET-CT can be critical to the accurate diagnosis of sequestration prior to pulmonary surgery.