老年人使用安眠鎮靜類藥物與複雜睡眠行為

Hypnosedative-induced Complex Sleep Behaviors in the Elderly

劉乃瑄(Nai-Syuan Liu) ； 周怡君(Yi-Jun Zhou) ； 黃宗正(Tzung-Jeng Hwang)

《台灣老年醫學暨老年學雜誌》 12卷4期 (2017/11) Pp. 225-235

https://doi.org/10.29461/TGG.201711_12(4).0001

摘要

安眠鎮靜類藥物是許多老年人常使用到的藥物，雖然老年人發生藥物副作用的機會較年輕人高出許多，可能的後果（如認知功能障礙、跌倒、甚至死亡等）也更嚴重，但由於睡眠障礙一直是許多老年人的困擾，這些藥物依然很常被使用在老年人身上。近年來在吃藥後發生複雜睡眠行為的報告增加，老年人由於睡眠結構、藥物感受性、身體功能退化等狀況，如果發生複雜睡眠行為，可能的危險性更高。因此，本篇就老年人使用安眠鎮靜藥物與可能發生複雜睡眠行為的機轉、危險因子、與處理方法做一個整理。

關鍵字

複雜睡眠行為 ； 老年人 ； 安眠鎮靜藥物

並列摘要

Hypnosedatives are often used in geriatric care in Taiwan, though the chance of adverse effects of these drugs, such as cognitive impairment, falls, and even death, is higher and the consequences of the adverse effects are much more serious in the elderly than in young people. Hypnosedatives, however, remains in use due to the high prevalence of sleep and mood problems in the elderly population. With a rise in the number of reported cases in recent years, hypnosedative-induced complex sleep behaviors have received increased attention. Complex sleep behavior, when occurs, places the elderly at a higher risk of severe morbidity or mortality because of their functional decline and the changes in their sleep architecture and drug sensitivity. We accordingly conducted a review of the use of hypnosedatives in the elderly and the mechanism, risk factors, and management of possible complex sleep behaviors.

並列關鍵字

complex sleep behaviors ； elderly ； hypnosedetives