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Immature Mediastinal Teratoma in Early Infancy: Report of One Case

幼嬰不成熟縱膈腔畸胎瘤:一病例報告

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摘要


本文報告一例自出生即有呼吸促迫、哭聲微弱、嘶啞現象的足月男嬰,經急救、插管後,一直依賴呼吸器。胸部X光上發現有一縱膈腔腫塊。此腫塊逐漸增大,到一個月大時已有明顯壓迫氣管、食道、心臟與上腔靜脈之現象。胸部超音波與電腦斷層檢查顯示腫塊爲一異質軟組織,含有局部鈣化和囊腫成份。病兒於58天大時接受手術,切除一6×4×4公分腫瘤,病理檢驗證實爲不成熟畸胎瘤。術後,病兒呼吸情況迅速改善。但是四個月後,追蹤胸部X光顯示上縱膈腔又出現腫塊,病兒遂接受第二次手術,切下胸腺組織和一0.8公分大小的成熟畸胎瘤。往後,病兒維持良好的情況。

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並列摘要


Immature mediastinal teratomas are rare, found in only 1% of all mediastinal teratomas; those occurring in the neonatal period are even more rare. A male baby suffering from tachypnea, weak crying and hoarseness since birth was noted, from a chest radiograph, to have a superior mediastinal mass. This mass enlarged progressively to an extent that the airway was threatened by one month of age. After resuscitation, intubation and mechanical ventilation, the infant became respirator-dependent. Chest computed tomography and ultrasonography revealed a heterogeneous cystic tissue mass containing focal calcifications. A well-encapsulated tumor, measuring 6×4×4 cm in size, located anterior to the thymus, was successfully removed at 58 days of age. The pathology showed an immature teratoma. After operation, respiratory distress dramatically improved. However, a superior mediastinal mass reappeared on a chest roentgenogram four months later. After a short course of chemotherapy, the infant received another operation to excise a mass composed of hypertrophic thymic tissue and a small nodular mature teratoma. The patient has remained well for more than nine months now.

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