Growing teratoma syndrome refers to retroperitoneal or other metastatic masses containing mature teratoma enlarging during chemotherapy for nonseminomatous germ cell tumors. Surgery is often difficult and early exploration optimizes the chance of resection which is necessary for long term survival. A case of the growing teratoma syndrome with metastatic masses in the retroperitoneum, lung and neck is presented. This patient was treated with surgery and systemic chemotherapy. Unfortunately, the patient died of respiratory failure due to huge metastatic tumor in the right intrathoracic cavity. Had the surgery been performed earlier, the patient could most likely have survived. Therefore, in cases of growing teratoma syndrome, surgical removal of the tumor should be done as early as possible.