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  • 期刊

Serotypes and Antimicrobial Susceptibility among Clinical Isolates of Pseudomonas Aeruginosa

綠膿桿菌的血清學分型及其藥物敏感性試驗

摘要


共有412株綠膿桿菌自病患的尿液〈77株〉,糞便〈65株〉,膿液〈125株〉,痰液〈117株〉,咽喉拭子〈4株〉,眼睛分泌物〈18株〉,和血液〈6株〉中分離所得,這些菌株以血清學分型加以分類,並探討每株綠膿桿菌的藥物敏感性試驗。經過血清學分型後,最常見的是屬於E型〈39.8%〉的菌株。同時,E型綠膿桿菌亦最常見於尿液〈44.2%〉,痰液〈43.6%〉,膿液〈40.0%〉,血液〈33.0%〉以及眼睛分泌物〈66.0%〉分離菌中。共有395株綠膿桿菌,分別測定其對於各種常用抗生素的敏感性程度。發現這些菌株對於chloramphenical及tetracycline全都具有抗藥性,而對cefsulodin全部皆具敏感性。除此之外,對piperacillin〈87.3%〉,ceftazidime〈92.7%〉,moxalactam〈79.0%〉,和enoxacin〈88.4%〉亦具高度的敏感性。同時,可見到來自尿道的綠膿桿菌所表現的抗藥性,比來自其它檢體的分離菌為高。另外,亦見到L型的菌株其抗藥性高於其他型別的菌株。

關鍵字

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並列摘要


Four hundred and twelve strains of Pseudomonas aeruginosa were isolated from urine (77 strains), stool (65 strains), wound pus (125 strains), sputum (117 strains), throat swab (4 strains), eye discharge (18 strains), and blood (6 strains) for serotyping and antimicrobial susceptibility testing. It was found that the most frequently isolated strains of P. aeruginosa belonged to serotype E (39.8%). In various clinical specimens, serotype E was significantly more frequent in the isolates derived from urine (44.2%), sputum (43.6%), wound pus (40.0%), blood (33.0%), and eye discharge (66.0%). In vitro susceptibility testing, all isolated strains tested (395 strains) of P. aeruginosa were resistant to chloramphenical and tetracycline, and were susceptible to cefsulodin. These isolates were also highly susceptible to piperacillin *87.3%), ceftazidime (92.7%), moxalactam (79.0%) and enoxacin (88.4%). It could be seen that urine-associated isolates exhibited more multiple resistance than those of other specimens. And strains of serotype L showed more resistance than other serotypes.

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