- 期刊
Mycobacterium Smegmatis Keratitis after Radial Keratotomy - A case Report
放射狀角膜切割手術後之Mycobacterium smegmatis角膜炎：病例報告
摘要
由分枝桿菌所引起的角膜感染病例有愈來愈多的趨勢，本文報告一位42歲女性病患接受放射狀角膜切割手術之後，左眼發生角膜潰瘍。經角膜擦刮抹片鏡檢發現許多可被抗酸染色快速染出的桿狀菌，經培養後證實為Mycobacterium smegmatis。就我們所知，這是文獻上首例由Mycobacterium smegmatis所造成的角膜炎，而藥物敏感試驗呈現對傳統的抗結核藥物及我們所測試的抗生素皆有抗藥性。此病人初期對Amikacin及Kanamycin的局部點眼治療有效，但不久後角膜浸潤再度增強，因此我們將藥物改為Amikacin及Ofloxacin的局部點眼治療，獲得令人滿意的結果，因此特提出此病例報告。
關鍵字
無資料並列摘要
A 42-year-old woman who developed a corneal ulcer in the left eye after radial keratotomy. The acid-fast stain showed that numerous clusters of acid-fast bacilli and Mycobacterium smegmatis were isolated on the culture. To the best of our knowledge, this is the first documented case of Mycobactevium smegmatis keratitis in the world literature. The sensitivity test showed that this organism resistant to all the anti-tubercubus agents and antibiotics we test. An initial response to amikacin and kanamycin was found, but relapse of infiltrate was noted one month later. The regimen was therefore changed to a combination of amikacin with ofloxacin. This patient had a favorable response to the topical therapy with amikacin and ofloxacin.
延伸閱讀
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