This article presents the nursing experience of caring for a child with posterior fossa syndrome after brain tumor surgery. Roy's adaptation model was used to evaluate the main health problems of children and their families during observation, physical evaluations, and interviews throughout the care period from January 17 to February 14, 2108. The identified health problems were high-risk infection, a speech communication disorder, fear, and family coping dysfunction. First, strategies including therapeutic play, interaction with a clown doctor, and participation in art classrooms were adopted to alleviate emotional adjustment disorders caused by expressive aphasia and to improve therapeutic interpersonal relationships. Subsequently, the child and parents were taught to rebuild communication channels by applying nonverbal communication skills; thus, they could regain their ability to cope with illness and restore their original family operations. This nursing experience can serve as a reference for other nursing staff.