Effect of Anoxic Anoxia on Propulsive Motility of the Small Intestine in Toads

高空缺氧對蟾蜍小腸推進運動之影響

方懷時(F. S. Fang)

《The Chinese Journal of Physiology》 19卷4期 (1966/06) Pp. 365-369

摘要

本實驗分兩項進行。
第一項比較蟾蜍在正常氧分壓下與在不同高度高空缺氧下之小腸推進動作對小腸全長百分比，則見在正常氧分壓下，小腸推進率高，在高空缺氧下低。高空缺氧抑制小腸推進動作，于是毫無疑問。而蟾蜍小腸推進動作之高空缺氧閥，則相當於高空三萬二千至三萬六千呎之間。
第二項分蟾蜍為四組（每組十隻）。第一組為對照組，第二組經腹淋巴囊接受溴化四乙銨注射，第三組為缺氧組（高空4000呎），第四組既接受溴化四乙銨注射，又受缺氧，則見溴化四乙銨如消除小腸外來神經之影響後，高空缺氧不能減弱小腸之推進動作，顯示缺氧對蟾蜍小腸平滑肌，並無直接影響，于是小腸外來神經之刺激，似為減弱小腸推進動作之主因。

並列摘要

Fang,. H.. S. Effect of anoxic anoxia on propulsive motility of the small intestine in toads. Chinese 3. Physiol., 19(4): 365-369, 1963-1966.-The effect of anoxia on the propulsive motility of the small intestine in toads was studied at the following partial pressures of oxygen: 52, 43, 36, .30 and 24 mmHg corresponding to simulated altitudes of 28000, 32000, 36000, 40000 and 44000 feet respectively. Essentially, charcoal-marker method was used. At a simulated altitude of 36000 feet or higher, there was a significant decrease in intestinal propulsive motility. The threshold laid between 32000 and 36000 feet. The possible mechanism of such a decrease in intestinal motility was discussed.