Impairment of Active Avoidance in Rats with Unilateral Hypothalamic Lesion

下視丘側部單側破壞引起之主動規避學習阻擾

蔡長添(C. T. Tsai) ； 詹肇州(C. C. Chan) ； 童起士(C. S.Tung)

《The Chinese Journal of Physiology》 22卷1期 (1975/12) Pp. 31-37

摘要

大白鼠經下視丘側部左邊或右邊單側破壞後，與對照組分別在双向穿梭籠內進行主動規避學習。每日每隻訓練二十次。各實驗組的正確反應率至第八天尚低於50％，而正常組於第五天卽已達到80％。此結果顯示主動規避學習之成功有依賴於下視丘側部的完整。

並列摘要

C. T. Tsai, C. C. Chan, and C. S. Tung Impairment of active avoidonce in rats with unilateral hypothalamic lesion. Chinese J. Physiol., 22(1): 31-37 1975. Male albino rats with unilateral hypothalamic (ULH) lesion on either the right or left side were trained to acquire active shock avoidonce in a two-way shuttle box. With 20 trials in a session per day, either group scored responses below 50% by the 8th day. while intact rats attained the criterion of 80% correct responses by the 5th day. It is concluded that intact lateral hypothalamic areas are essential for successful learning of active shock avoidance.

並列關鍵字

Lateral hypothalamus ； Shock avoidance ； Unilateral hypothalamic lesion