Insufficient toughness and low reduction ratio at the center of heavy plate along thickness direction are two main defects in the UT (ultrasonic testing) results. That the defects were caused by centerline segregation and porosities at the center of thickness direction of continuously cast slabs have been confirmed. Several countermeasures, for example uniform distribution of spray pattern, intentional bulging and soft reduction, low superheat casting and increase of specific water ratio etc., were made to solve the above-mentioned problems and consequently quality cast slabs were produced. It was concluded that the low superheat (below 12°C) casting is the most effective measure to improve the quality of heavy plate steel. At present, a standard practice of continuous casting process for heavy plate steel was established.