Obesity and Changes in Body Weight Related to 10-Year Diabetes Incidence in Women in Taiwan (1993-2003)

臺灣女性肥胖及體重增加與10年後糖尿病發生率的相關

Lee-Ching Hwang ； Chien-Jen Chen ； Boniface J Lin

《Asia Pacific Journal of Clinical Nutrition》 16卷4期 (2007/12) Pp. 677-682

https://doi.org/10.6133/apjcn.2007.16.4.13

摘要

研究目的在探討成人期肥胖與體重增加是否影響第二型糖尿病的發生率，本研究對象為954位女性（平均年齡37.1±9.6歲），自1993年起至2003年定期健康檢查，追蹤10年之後發現第二型糖尿病的發生率為每千人年3.64，發生糖尿病的人之中有16.6%是屬於體重過重，而56.7%是肥胖者，身體質量指數超過25 kg/m^2的人發生第二型糖尿病的危險性是身體質量指數介於18－22.9 kg/m^2的10.4倍。體重增加亦是發生第二型糖尿病的高危險群，每增加一公斤體重可以增加16%的風險，在女性成人期若是能避免體重過重或是肥胖，並維持適當體重有利於預防第二型糖尿病。

關鍵字

肥胖 ； 身體質量指數 ； 體重改變 ； 發生率 ； 第二型糖尿病 ； 臺灣

並列摘要

This study aimed to investigate the relation of obesity and changes in body weight through adulthood with risks of type 2 diabetes. This study of 954 middle-aged women free of diabetes (mean age, 37.1±9.6 years) was conducted in a hospital. The baseline and biannual health check-ups were performed from 1993 to 2003. The cumulative incidence rate of type 2 diabetes was 3.64 per 1000 person-years during the mean follow-up period of 10 years. 73.3% of subjects who developed type 2 diabetes were overweight (16.6%) or obese (56.7%). Obese subjects (body mass index more than 25 kg/m^2) had a relative risk of type 2 diabetes of 10.4 (95% confidence interval 2.95-36.9) compared with subjects with an optimal body mass index (18-22.9 kg/m^2). Long-term weight gain was strongly related to the risk of type 2 diabetes. Each 1 kg of weight gain was associated with a 16% increase in risk of developing diabetes. This study indicated that obesity at young adult and weight gain appreciably increase risk for type 2 diabetes. Maintaining a lean weight throughout adulthood seems to be beneficial in the primary prevention of type 2 diabetes.

並列關鍵字

obesity ； body mass index ； weight change ； incidence ； type 2 diabetes ； Taiwan