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Chronic Neutrophilic Leukemia-Analysis of 31 Reported Cases

慢性中性球白血病─31個文獻病例分析報告

摘要


一名77歲之中國男性被診斷確定為慢性中性球白血病(CNL)。患者之臨床表現為成熟之中性白血球增多,脾臟腫大,白血球鹼性磷酸酶分數升高,血清維生素B12及尿酸增高,骨髓呈現骨髓球系細胞增生及陰性之費城染色體,患者並無感染或惡性病之證據足以懷疑其為類白血病反應,其中性白血球功能呈現吞噬活力減少,骨髓過氧酶含量減少及刺激後醇素釋出增加之現象。CNL為一罕見之疾病,從文獻中連本病例共31例作一分析報告。

並列摘要


A 77-yr-old Chinese man was diagnosed as chronic neutrophilic leukemia (CNL). The patient showed sustained mature neutrophilic leukocytosis, splenomegaly, high leukocyte alkaline phosphatase score, elevated serum vitamin B12 and uric acid, myeloid hyperplasia and absence of philadelphia chromosome in the bone marrow. There was no evidence of any underlying infection or malignancy to be considered that this condition was a leukemoid reaction. The neutrophil function showed decreased phagocytic activity, decreased myeloperoxidase content and increased release of the enzyme after stimulation. CNL is not a common disease, literature review and analysis of 31 cases will be reported.

被引用紀錄


康閎森(2012)。二氧化碲電阻式記憶體之研究〔碩士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2012.03175

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