We report a 5-year-6-month-old case of pneumonia complicating with septic shock and acute respiratory distress syndrome. He was successfully treated with extracorporeal membrane oxygenation (ECMO). Veno-arterial mode of ECMO was used at first and it was shifted to veno-venous mode of ECMO after hemodynamics were stabilized. Total supporting duration of ECMO was 684 hours. The patient is well now, in functional class I of the New York Heart Association.