Epithelioid Hemangioendothelioma of the Liver: Report of a Case

肝臓類上皮性血管內皮瘤：一病例報告

黃瑩如(Ying-Ju Huang) ； 霍德義(Teh-Ia Huo) ； 李潤川(Rheun-Chuan Lee) ； 賴瓊如(Chung-Ru Lai) ； 張扶陽(Full-Young Chang)

《臺灣消化醫學雜誌》 19卷4期 (2002/12) Pp. 250-256

https://doi.org/10.6557/GJT.200212_19(4).0002

摘要

一位46歲女性，因右上腹痛已六個月而接受身體檢查。理學檢查發現右上腹壓痛，肝功能指數偏高，輕微的AFP和CA-125偏高，腹部超音波發現一大型肝腫瘤占據肝臟兩葉，腹部電腦斷層及血管攝影發現多發的肝腫瘤，病理切片顯示腫瘤組織之免疫染色為Ulex Europaeus I lectin 陽性並證實為類上皮性血管內皮瘤。本例因腫瘤為肝臟內多發性且供應腫瘤之血管不豐富，未接受手術切除或動脈栓塞治療。病人在診斷後一年因與法接受肝移植而因食道靜脈曲張破裂大量出血而死亡。本文藉此病例介紹此一罕見原發肝臟腫瘤的臨床表現、影像學特徵、治療及預後。

關鍵字

類上皮性血管內皮瘤 ； 肝臓腫瘤 ； 食道靜脈曲張

並列摘要

Epithelioid hemangioendothelioma of the liver is a rare primary hepatic malignancy of vascular origin. We report a 46-year-old female patient with the initial presentation of right upper quadrant pain for six months. A series of imaging studies, including abdominal sonography, computed tomography and celiac angiography showed multiple tumor masses in both lobes of liver Microscopically, the biopsied specimen was positively immunostained with Ulex Europaeus I lectin (UEAI), which was characteristics for epithelioid hemangioendothelioma. Surgical resection and transcatheter arterial embolization were not suitable for this patient because of the nature of multicentric involvement in liver and low vascularity of the tumor Patient died of massive esophageal varices bleeding one year after the diagnosis while waiting for liver transplantation. Literature regarding this rare disease were reviewed in this report.

並列關鍵字

epithelioid hemangioendothelioma ； liver tumor ； esophageal varices