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Synchronous Colon Adenocarcinoma with High-Grade Gastric Maltoma: Report of a Case

同發性大腸腺癌與胃粘膜相關淋巴組織瘤:一病例報告

摘要


自從西元1889年第一例被發表以來,多發性原發癌漸漸被大家所熟悉,並且吸引研究人員的注意。多發性原發癌的發生率也與日俱增。研究顯示大腸癌與胃粘膜相關淋巴組識瘤發生第二原發癌的機會都相當高。然而兩者同時發生的機會卻相當罕見。一例69歲女性因裹急後重及解血便,經大腸內視鏡診斷為乙狀結腸癌,入院接受手術治療。手術中外科醫師注意到在胃的大彎處有另一腫瘤。於手術中立即施行胃內視鏡檢,發現於胃下體部大彎處有一潰瘍性病變。冷凍切片檢查結果是良性潰瘍。由於高度懷疑是惡性腫瘤,經與家屬溝通後,同時施行次全胃切除。病理報告證實為一例罕見之多發性原發癌-同發性大腸腺癌與高度胃粘膜相關淋巴組織瘤。據我們所知,此為文獻中第一個被報告的病例。

並列摘要


Multiple primary cancers have became more and more familiar and attractive to the physicians since first description in 1889. The incidence of the cancers has increased with an almost exponential rate. Both colon cancer and gastric MALToma are associated with high incidence of second neoplasms. But the combination of both is rare. A 69-year-old female, suffering from tenesmus and bloody stool passage, was admitted for management of a sigmoid cancer. During operation, an indurated gastric mass with torturous vessels on serosa was seen. The panendoscopy performed immediately and assured an ulcerative tumor on the greater curvature side of the lower body. The frozen section biopsy from the ulcer margin manifested a benign ulcer. After the discussion with her families, subtotal gastrectomy was implemented for the highly suspected malignant tumor. The final pathology perceived a rare case of synchronous sigmoid adenocarcinoma with high grade gastric MALToma. The patient is well and free from tumor recurrence one year after surgery. To our knowledge, the two tumors of this kind is first reported in the literatures.

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