Gastric Carcinoid Tumor Associated with Autoimmune Atrophic Gastritis: Report of a Case

自體免疫萎縮性胃炎相關之胃類癌瘤：一病例報告

黃百寬(Pai-Kuan Huang) ； 楊旻達(Min-Ta Yang) ； 廖麗瑛(Li-Ying Liao) ； 張廷安(Ting-An Chang)

《臺灣消化醫學雜誌》 28卷1期 (2011/03) Pp. 34-39

https://doi.org/10.6557/GJT.201103_28(1).0005

摘要

胃類癌瘤(gastric carcinoid tumor)是一種罕見的內分泌腫瘤，源自於胃內類腸嗜鉻細胞(enterochromaffin-like cell)，常偶然發現於常規的胃鏡檢查。我們報告一位58歲女性，過去有Graves' disease及萎縮性胃炎的病史，因數週的上腹不適再次進行胃鏡檢查偶然發現胃體部有多發性胃息肉，病理報告證實爲胃類癌瘤。進一步抽血報告顯示胃泌素高達1433 pg/mL以及壁細胞抗體(anti-parietal cell antibody)陽性，而診斷爲第一型胃類癌瘤。雖然第一型胃類癌的病程遲緩且預後良好，但是死亡率似乎仍不能忽略。我們建議應例行性以上消化道內視鏡追蹤病灶大小變化。

關鍵字

胃類癌瘤 ； 萎縮性胃炎

並列摘要

Gastric carcinoid (GC) tumor is a rare neuroendocrine tumor, which derives from gastric enterochromaffin-like (ECL) mucosal cells. It is usually found incidentally by routine endoscopy. We present a 58-year-old female with past history of Graves' disease and atrophic gastritis who underwent upper gastrointestinal (UGI) endoscopy due to epigastralgia for one week. After removal of multiple polyps in gastric body, GC tumor was diagnosed histologically with specific immunohistochemical staining. In addition, type 1 GC classification was confirmed by elevated serum gastrin level to 1433 pg/mL and presence of anti-parietal cell antibody. Although the clinical course of type 1 GC is indolent and the prognosis is good, the mortality rate seems innegligible. Therefore routine follow-up may be necessary to monitor the size progression.

並列關鍵字

gastric carcinoid tumor ； autoimmune atrophic gastritis