Large Cell Neuroendocrine Carcinoma of the Stomach: A Case Report

胃大細胞神經內分泌癌：病例報告

石志安(Chih-An Shih) ； 蔡峯偉(Feng-Woei Tsay) ； 黎國洪(Kwok-Hung Lai) ； 游偉雯(Wei-Wen Yu) ； 許秉毅(Ping-I Hsu)

《安泰醫護雜誌》 18卷3期 (2012/09) Pp. 51-61

https://doi.org/10.7078/TSMHMNJN.201209.0051

摘要

在臨床上原發性胃大細胞神經內分泌癌發生在成人為非常罕見。我們的病例報告內容中描述一位74歲男性病患，因腹脹及體重減輕等症狀，且持續有三週之久而住院檢查。理學檢查中無發現腹部腫塊或腹痛。上消化道內視鏡檢中發現一顆約3.0公分胃腫瘤，其病灶位於胃體部中段及偏前側位置。腹部電腦斷層檢查發現一顆約3.3公分位於胃體部中段之腫瘤，伴隨表面潰瘍及輕度顯影狀態。無發現淋巴結及鄰近器官轉移之情形。在腹部手術過程中，發現一顆約3.4公分胃體部中段之腫瘤。其病理診斷為原發性胃大細胞神經內分泌癌。同時，患者接受半胃切除手術及淋巴結廓清術。在術後追蹤一年後，目前並無復發之情形。

關鍵字

胃腫瘤 ； 神經內分泌瘤 ； 癌

並列摘要

Primary gastric large cell neuroendocrine carcinoma (LCNEC) in adults is extremely rare. This report presents a 74-year-old male with a gastric LCNEC. He experienced abdominal fullness and body weight loss for 3 weeks. Physical examination showed no palpable abnormal mass or abdominal tenderness. Upper endoscopy revealed a polypoid mass, approximately 3.0 cm in diameter, located in the anterior wall of the middle gastric body. Abdominal computed tomography showed a mildly enhanced, broad-based mass with central ulceration, measuring about 3.3 cm in diameter in the mid-body of the stomach without lymphadenopathy and positive findings for adjacent organs. On surgery, a gastric mass of approximately 3.4 cm in diameter was excised from the gastric middle body along the anterior wall. Final pathological diagnosis was consistent with an LCNEC originating from the gastric wall. Radical subtotal gastrectomy with lymph nodes dissection was performed. No tumor recurrence was noted after 1-year follow-up.

並列關鍵字

stomach neoplasm ； neuroendocrine tumor ； carcinoma