Intraocular Manifestations of Non-Hodgkin Lymphoma

目的：本研究的主旨仍在研究台灣非霍金杰氏淋巴瘤病患的各種眼內表現。病人及方法：本文作者迴溯分析自民國八十年至民國八十八年，所有國立台灣大灣附設醫院組織學診斷為非霍金杰氏淋巴瘤，並壞疑有眼球淋巴瘤侵犯的病患的眼球表現及病史。結果：過去八年中共有六名非霍金杰氏淋巴瘤的病患為發現眼內表現。其中一位病患為中樞神經性非霍金杰氏淋巴瘤，其表現為虹彩炎合併類中心滲出性脈絡膜網膜炎，而其眼內表現早於中樞神經系統表現。有五名病患為全身系統性非霍金杰氏淋巴瘤。其眼內表現包括類白血病網膜病變、全身系統性非霍金杰氏淋巴瘤的病患，其眼內表現均晚於全身系統性表現。結論：根據本研究的六名病例，非霍金杰氏淋巴瘤病患的眼內表現為多樣性，且眼內症狀可能晚於或早於全身性症狀。臨床診斷懷疑為非霍金杰氏淋巴瘤的病患若能接受仔細的眼科學檢查，不但有益於早期確定診斷，且可以提早施予適當的治療。(慈濟醫學 2000;12:77-85)

關鍵字

非霍金杰氏淋巴瘤；眼內腫瘤；眼內淋巴瘤；葡萄膜炎；中樞神經系統性淋巴瘤

並列摘要

Objective: This study aimed to describe the various ocular presentations of systemic non-Hodgkin lymphoma and non-Hodgkin lymphoma of the central nervous system in Taiwan. Patients and Methods: The authors reviewed the medical and ophthalmologic records of all patients with histopathologically proven non-Hodgkin lymphoma with suspected intraocular involvement who presented at National Taiwan University between 1991 and 1999. Results: There was one patient with non-Hodgkin lymphoma of the central nervous system in the study who presented with vitritis with central serous choroidoretinopathy (CSCR)-like sensory retinal detachment as the first manifestation of lymphoma. Five cases of systemic non-Hodgkin lymphoma were found. The patients’ ocular manifestations included leukemia-like retinopathy, panuveitis, leopard-spot macular lesions, multifocal choroiditis-like lesions and subretinal elevated mounds with vitritis. Ocular manifestations all occurred secondary to systemic lymphoma. Conclusions: Based on these cases, ocular manifestations of non-Hodgkin lymphoma may present with a wide variety of clinical features. Careful ocular examinations of patients suspected to have non-Hodgkin lymphoma are invaluable because they may lead to early diagnosis and optimal management. (Tzu Chi Med J 2000; 12:77-85)

並列關鍵字

non-Hodgkin lymphoma ； ocular neoplasm ； intraocular lymphoma ； uveitis ； central nervous system lymphoma

國際替代計量

Intraocular Manifestations of Non-Hodgkin Lymphoma

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