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Ossification of the Auricles - A Forgotten Sign of Adrenal Insufficiency

耳殼骨化-腎上腺低能症中被遺忘的症狀

摘要


臨床上,耳殼骨化是罕見的臨床症狀。通常軟組織的異位性鈣化是源自於組織受到外傷後,鈣離子沉積造成的結果。最常見於局部耳朵外傷、凍傷及因拳擊造成耳朵傷害等情形。雖然是異位性的鈣化現象,但鈣化的成份與正常的骨質無異。而在引起耳殼鈣化的全身性疾病中,原發性腎上腺低能症(愛迪森氏症)是最常見的原因。但續發性的腎上腺低能症合併耳殼骨化者,文獻只有三例報告。我們報告一例腦下垂體低能症,合併續發性的腎上腺低能症及耳殼骨化,希望此一在腎上腺低能症中被遺忘的症狀於理學檢查時應該受到重視。

並列摘要


Auricular ossification is a rare clinical entity. Dystrophic calcification of soft tissue or cartilage is the result of calcium deposition in damaged tissues. The most common causes of this phenomenon are local trauma, frostbite, and boxing. However, the elemental content of ossified auricular cartilage is similar to that of normal bone specimens. Primary adrenal insufficiency (Addison’s disease) is the most frequent systemic disorder associated with auricular calcification. Only three cases of auricular calcification have been reported in patients with secondary hypoadrenalism. We report a 43-year-old patient of auricular ossification with hypopituitarism and secondary hypoadrenalism to remind clinicans of this somewhat forgotton sign of adrenal insufficiency.

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