並列摘要
Primary malignant melanoma of the vagina is a very rare gynecologic malignancy and limited data are available on which to base recommendations for the primary management of patients. The tumor is primarily found in the distal one-third (58%) of the vagina and mostly on the anterior wall (45%). A low occurrence of this type of tumor makes the assessment of various treatment options difficult. There are several treatment options but none of them is proved to be standard approach. As treatment options, there are some standard modalities used individually or in combination, such as conservative wide local excision, radical surgical extirpation, irradiation and chemotherapy. The spectrum of surgical therapy ranges from conservative surgery such as wide excision of the lesion or total vaginectomy to radical extirpation with en bloc removal of involved pelvic organs. Regardless of the extent of primary surgery, positive histological margins or presence of melanoma in situ at the edge of the specimen result in a higher incidence of recurrence and poorer survival rates. The role of elective lymph node dissection remains controversial. The dissection of lymph nodes that are clinically negative for melanoma of the vagina is debatable. The indication of evaluation of pelvic nodes is also debatable.
延伸閱讀
- Chung, S. D., Liao, C. H., Shun, C. T., Tai, H. C., & Chueh, S. C. (2006). 陰莖惡性黑色素瘤. 臺灣泌尿科醫學會雜誌, 17(4), 140-143. https://www.airitilibrary.com/Article/Detail?DocID=10163220-200612-17-4-140-143-a
- Tsai, C. H., Wang, K. C., & Tzeng, C. C. (2007). 原發性肛門直腸黑色素瘤－病例報告. 秀傳醫學雜誌, 7(4), 157-160. https://www.airitilibrary.com/Article/Detail?DocID=15610497-200712-7-4-157-160-a
- 蔡宗合、郭錦彰、郭乃文、徐正雄（1998）。結膜惡性黑色素細胞瘤－病例報告。中華民國眼科醫學會雜誌，37(3)，304-308。https://doi.org/10.30048/ACTASOS.199809.0012
- 黃潔貞（2008）。漫談惡性黑色素瘤。臺灣醫界，51(7)，28-29。https://doi.org/10.30044/TMJ.200807.0005
- Huang, H. K., Liu, I. F., Ho, C. L., Chou, C. Y., & Cheng, Y. M. (2005). Primary Vaginal Amelanotic Melanoma. Taiwanese Journal of Obstetrics & Gynecology, 44(2), 177-179. https://doi.org/10.29787/TJOG.200506.0015