原發性鰓源性鱗狀細胞癌

Primary Branchiogenic Squamous Cell Carcinoma

李順源(Soon-Yean Lee) ； 賴銘堂(Ming-Tang Lai) ； 楊景勛(Ching-Hsun Yang) ； 李飛鵬(Fei-Peng Lee)

《台灣耳鼻喉頭頸外科雜誌》 42卷1期 (2007/02) Pp. 20-24

https://doi.org/10.6286/2007.42.1.20

摘要

狀細胞癌(squamous cell carcinoma)原發於鰓裂囊腫(branchial cleft cyst)的病例十分罕見。自1950年Martin等提出原發性鰓源性鱗狀細胞癌之鑑定標準後，僅極少數符合鑑定標準的病例被發表於文獻。本文報告一名37歲女性病例，於右頸鰓裂囊腫之診斷下，接受鰓裂囊腫切除手術。病理報告符合Martin等所訂4項鑑定標準之罕見鰓裂囊腫原發性鱗狀細胞癌病例。術後追蹤滿8年，無復發現象，亦無身體其他部位之鱗狀細胞癌。鰓裂囊腫之原發性癌之術前診斷十分困難；術後之病理診斷亦易因是否為原發性而有爭議；術後之追蹤檢查更是不易。治療上除了局部廣泛切除、頸部廓清術和放射線治療外，仔細尋找身體其他部位有否潛藏性的原發惡性腫瘤十分重要。

關鍵字

鱗狀細胞癌 ； 鰓裂囊腫

並列摘要

Squamous cell carcinoma that primarily arises in a branchial cleft cyst is very rare. Our case concerns a female patient who received resection of branchial cleft cyst under the impression of a branchiogenic tumor of the right neck. Histological evaluation of the mass revealed a cystic structure lined by carcinomatous squamous epithelium that showed pleomorphism and frequent mitosis. The patient remains disease-free eight years after the operation. In 1950, Martin et al. published four criteria for the diagnosis of primary branchiogenic carcinoma. This case fulfills all of the four branchiogenic carcinoma criteria established by Martin et al. Modalities of treatment of the disease include a wide local excision, radical neck dissection and radiotherapy. In addition, the patient should be fully investigated to exclude other primary head and neck tumors.

並列關鍵字

squamous cell carcinoma ； branchial cleft cyst