摘要
口腔腺樣鱗狀上皮細胞癌在分類上是鱗狀上皮細胞癌變異中非常少見。因為棘皮層鬆解，組織型態呈現偽腺體狀或是偽血管狀是主要特徵。腺樣鱗狀上皮細胞癌好犯位置常在陽光照射的皮膚，出現於上呼吸消化道黏膜的腺樣鱗狀上皮細胞癌非常罕見。黏膜的腺樣鱗狀上皮細胞癌預後極不好，本院兩例腺樣鱗狀上皮細胞癌都在術後短時間復發且死亡，因病例罕見故提出報告討論。
並列摘要
Oral acantholytic squamous cell carcinoma (ASCC) is an uncommon but well-recognized variant of squamous cell carcinoma. In histology, ASCC are quiet different with typical oral squamous cell carcinoma. Acantholysis of tumor cell lead to the formation of anastomosing spaces (pseudo-vascular like pattern) and channels (pseudo-glandular like pattern). ASCC often occurred in areas of the skin exposed to the sun light. Some literatures have been reported that ASCC have occurred in the skin of the head and neck. However, it has only rarely been documented in the upper aerodigestive tract mucosa. Its prognosis in the mucosa is controversial, with some reports suggesting more aggressive behavior and worse prognosis. Due to the few number of cases, there is no conclusive result. In our hospital, the two ASCC cases have poor prognosis due to recurrence in short time. Since it was rare in oral mucosa of head and neck region, we present these cases.
延伸閱讀
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