摘要
脂肪肉瘤(liposarcoma)是源自間葉細胞的惡性腫瘤，好發於四肢深層軟組織以及後腹腔，發生在頭頸部不及5%。頭頸部之脂肪肉瘤因為生長緩慢，初期症狀多以無痛腫塊表現，少部分起因於腫塊過大造成局部疼痛，或因壓迫造成呼吸困難和吞嚥不適。病理上分為5種形態，以圓細胞型(round cell)和多形型(pleomorphic)為較惡性。好發於頭頸部的脂肪肉瘤則以分化良好型和黏液樣型居多。本病例報告為－24歲男性病患，主訴左前頸腫塊兩週，合併壓痛感，電腦斷層呈現左側甲狀腺一實質性腫塊合併局部氣管壓迫，經手術完整取出腫塊，病理報告證實為合併黏液樣及圓細胞型的脂肪肉瘤，術後接受全身骨骼掃描及腹部超音波檢查無異狀。因為脂肪肉瘤在頭頸部少見，而黏液樣合併圓細胞脂肪肉瘤在頭頸部更屬罕見，特提出報告。
並列摘要
Liposarcoma is a malignant tumor differentiated from mesenchymal origin, which commonly affects the extremities and retroperitoneum and makes up 9.8-16% of all soft tissue sarcoma. Head and neck liposarcoma, compared to other regions, has a prevalence rate of less than 5% and are usually symptom-free upon initial presentation. Pain and functional disturbance may occur with increasing tumor size. According to histopathological classifications from the World Health Organization five variants, namely well-differentiated, myxoid, round cell, pleomorphic, and mixed types, can be differentiated. In our report we present a case of anterior neck liposarcoma of both myxoid and round cell types in a 24-year-old male. Due to its low prevalence rate and rare histopathological pattern, it is worthy of mention.
延伸閱讀
- 邱俊偉、游進益、曾慶誠（2005）。成人頸部橫紋肌肉瘤。台灣耳鼻喉頭頸外科雜誌，40(4)，148-153。https://doi.org/10.6286/2005.40.4.148
- Hung, J. J., & Hsu, W. H. (2007). 前縱膈腔之巨大脂肪瘤. 胸腔醫學, 22(5), 351-354. https://doi.org/10.29806/TM.200710.0008
- Chen, C. J., Lai, F. M., Chen, V. T. K., & Chang, T. M. (1997). 異型新生之後腹腔脂肪肉瘤. Journal of Medical Sciences, 17(5), 305-310. https://www.airitilibrary.com/Article/Detail?DocID=10114564-199704-201306110036-201306110036-305-310
- 趙俊智、黃國衛、陳中仁、吳介仁、趙文元（2013）。舌部脂肪肉瘤。台灣耳鼻喉頭頸外科雜誌，48(2)，176-179。https://doi.org/10.6286/2013.48.2.176
- 吳志昶、方深毅、靳應台（1992）。Castleman's Disease in the Neck － Case Report。中華民國耳鼻喉科醫學會雜誌，27(4)，396-400。https://doi.org/10.6286/1992.27.4.396