Iridocorneal Endothelial Syndrome-Clinical Observation and Treatment

虹膜角膜內皮症候羣之臨床觀察及治療

傳堯安(Yao-An Fu) ； 陳賢立(Shen-Lin Chen)

《中華民國眼科醫學會會刊》 27卷1期 (1988/05) Pp. 234-242

https://doi.org/10.30048/ACTASOS.198805.0042

摘要

本文收集15例（20隻眼）虹膜角膜內皮症候羣之病例，其中4例為男性，11例為女性，平均年齡為38.7歲。追踪期限由6個月到10年不等。
視覺障礙為最常見之主訴。臨床特徵有角膜水腫及其內皮細胞異常。所有患眼均有不同程度之瞳孔異位及周邊前黏連。我們根據虹膜萎縮之程度及孔洞產生之有無，區分為五組。另一較特殊之現象為有4隻眼之水晶體表面有色素附著，但無眼內發炎之證據。
治療方面，有6隻眼須施行小樑切除術，但在術後眼壓正常的情形下，其中2眼仍有持續性之水疱角膜病變。

並列摘要

Fifteen patients (4 men and 11 women ranged in age from 19 to 70 years) of the iridocorneal endothelial syndrome were reviewed retrospectively in this study. In total 20 eyes, there were 3 eyes with Chandler's syndrome, 14 eyes with progressive iris atrophy and 3 eyes with Cogan-Reese syndrome. The duration of the follow-up was from 6 months to 10 years.
Visual disturbance was the most common chief complaint. Specular microscopy revealed corneal endothelial abnormalities in 10 examined eyes. Variable degree of corectopia and peripheral anterior synechia occurred in all eyes. Atrophy of the iris associated with hole formation were described and classified into five groups. Pigment on the anterior lens surface was present in 4 eyes.
Penetrating keratoplasty was done in one eye. Trabeculectomy was performed in 6 eyes. Intraocular pressure was well-controlled with or without medication. Two eyes had persistent bullous keratopathy after surgery.

並列關鍵字

Chandler's syndrome ； Progressive iris atrophy ； Cogan-Reese syndrome ； Gonioscopy