視網膜色素層代償不全之臨床表徵以及其雷射治療之經驗

The Clinical Features of Retinal Pigment Epithelium Decompensation and the Experience of It's Laser Treatment

吳文權(Wen-Chen Wu) ； 林嘉祥(Chia-Hsiang Ling) ； 蔡榮坤(Rong-Kung Tsai) ； 鄭淑珠(Shwu-Ju Jeng)

《中華民國眼科醫學會會刊》 27卷2期 (1988/05) Pp. 739-747

https://doi.org/10.30048/ACTASOS.198805.0133

摘要

收集已發生視網膜色素層病變之27個CSCR病例（30隻眼）進行研究，發現視網膜色素層代償不全（Retinal Pigment Epithelium Decompensation，簡稱RPED）為繼發於此等CSCR色素層病變之獨立而特殊的臨床實體(clinical entity)，其主要特徵有二：(1)以眼底鏡觀察眼底之後極部並沒有很明顯之病理變化。(2)在眼底螢光攝影之初期即出現transmission defect，而在螢光攝影之末期又出現RPE staining。
本報告除了描述RPED之臨床表徵之外，並依照RPE staining之位置與性質分成4種類型以評估其視力變化之情形。另外有8隻眼睛因視力逐漸惡化而接受雷射治療，其中有5眼(62.5%)視力改善，2眼(25%)視力不變，1眼(12.5%)因新增血管之產生而視力惡化。我們的結論是當RPED之late staining位於中心小凹無虹管區(FAZ)邊緣或外邊時，一旦發生視力惡化的情形便可以考慮作雷射治療。

並列摘要

From November 1, 1986 to October 30, 1987, we had collected 30 cases of retinal pigment epithelium decompensation. (at the Ophthalmological Department of Kaohsiung Medical College) Our study demonstrates that retinal pigment epithelium decompensation is a clinical entity closely related to central serous chorioretinopathy. Retinal pigment epithelium decompensation has a typical fluorescein angiographic pattern that distinguishes it from other diseases of the retinal pigment epithelium. The natural course of RPED depends on it's specific type. Photocoagulation can be considered in cases where visual acuity is progressively deteriorating and if the area of decompensated RPE is outside the FAZ or located at the margin of FAZ.

並列關鍵字

central serous chorioretinopathy ； retinal pigment epithelium decompensation ； fluorescein angiography ； photocoagulation