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角膜蟹足腫-病例報告

Corneal Keloid-A Case Report

摘要


角膜蟹足腫(Corneal Keloid)是相當罕見的疾病。如同其他部位的蟹足腫,它是身體組織一種「過度增生」的反應,在病理上具有纖維血管性增生(fibrovascular proliferation)及輕度發炎的特徵。本文提出一個穿孔性角膜潰瘍引起的角膜蟹足腫。病灶為角膜上圓形,隆起的斑塊,表面有細小血管。病理特徵為雜亂而表皮化的上皮,充滿不規則膠原纖維,纖維母細胞、血管及紅彩色素的基質。鮑氏膜,台斯梅氏膜,內皮層皆消失不見。有輕度炎性細胞浸潤,但組織中並無皮膚附屬器存在。本文並討論有關文獻中此疾病的臨床表現,病理特徵,致病原因及治療。

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並列摘要


We reported a corneal keloid in a 6-year-old girl with previous perforated corneal ulcer. The lesion was a round, elevated, pinkish-white nodule on left central cornea. Histologically, this nodule had disorganized, epidermalized epithelia. Stromal tissue was occupied by irregularly arrayed collagen fibers, fibroblasts and a few inflammatory cells. Normal laminar pattern was disturbed. Vessels of varying calibers interspersed in the stroma. Iris lined the posterior surface of cornea and some iris pigments could be found in the stroma. Bowman's layer, Descemet's membrane, endothelia were all absent. No dermal appendages were found. After penetrating keratoplasty, the patient is doing well.

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