- 期刊
Fungal Keratitis Caused by Candida Utilis - Case Report
Candida Utilis引起之角膜潰瘍－病例報告
摘要
Candida utilis為一種工業使用之酵母菌，一般認為不致造成人體病變。直到1988年及1993年兩篇報告指出：在某些情況下，此菌也可能造成人體真菌血症。吾人報告此菌首例侵犯眼睛造成角膜潰瘍的病例，並描述其臨床表徵及角膜抹片所見。基本上，C.utilis引起之角膜潰瘍，與一般黴菌性角膜潰瘍的臨床表徵並無異。但因其致病性較弱，故患處局部性反應較緩和，而抗黴菌藥物fluconazole和amphotericin B的治療效果也相當好。患者在接受治療三週後完全痊癒，並在接受角膜移植手術後維持相當有用的視力。吾人推論：在抗生心及類固醇被廣泛使用下，此菌可能成為真菌性角膜潰瘍之病原體之一。
關鍵字
無資料並列摘要
We report the first case of an ocular fungal infection caused by Candida utilis in a 72-year-old woman. Although candidiasis is the most common opportunistic fungal infection in humans, C. utilis had not been associated with human morbidity until two cases of fungemia were reported in 1988 and 1993, The clinical features exhibited typical feather-like infiltration at the ulceration margin of this case. After treatment with topical fluconazole and amphotericin-B, the ulceration healed within 3 weeks. The patient underwent penertrting keratoplasty and regained useful vision. We concluded that C. utilis is a new corneal pathogen and should be included in the differential list of mycotic keratitis.
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