穿孔性暨瀕穿孔性角膜潰瘍之治療

The Management of Perforated and Preperforated Corneal Ulcers

蕭維鈞(Wei-Chun Hsiao) ； 曾順輝(Sung-Huei Tseng)

《中華民國眼科醫學會雜誌》 32卷4期 (1993/12) Pp. 472-478

https://doi.org/10.30048/ACTASOS.199312.0013

摘要

本篇回溯性收集1989年1月至1993年9月，成大醫院之穿孔性角膜潰瘍(perforated corneal ulcers)暨瀕穿孔性角膜潰瘍(preperforated corneal ulcers)之病例計54例，就其病因、致病菌、治療方法、以及術後後遺症做一分析比較。結果發現組織黏膠(tissue adhesives)治療成功佔39%(21/54)，先組織黏膠處理，再行角膜移植佔15%(8/54)，嵌片式移植(patch graft)佔15%(8/54)，直接角膜移植僅5%(3/54)，顯示組織黏膠為處理穿孔性暨瀕穿孔性角膜潰瘍最常用且簡單有效之方法。

並列摘要

The perforated and impending perforated corneal ulcers, which are difficult to deal with, can occur secondary to various corneal disorders. Medical treatment, simple patch, therapeutic contact lens, tissue adhesives, tarsorrhaphy, patch graft, conjunctival flap, or penetrating keratoplasty may be indicated according to the severity of the lesions. Herein, we report our experience in the management of 54 cases of perforated and preperforated corneal ulcers from Jan. 1989 to Sep. 1993 in NCKUH and evaluate the effect of our therapeutic approaches. Our results revel 21 cases (39%) treated with tissue adhesive successfully. 8 cases (15%) should undergo therapeutic penetrating keraoplasty after tissue adhesive applied initially. Another 8 cases (15%) received patch graft surgery and only 3 cases (5%) need direct penetrating keratoplasty. It appeared that tissue adhesive application is a simple and effective measure in treating most minor perforated and preperforated corneal ulcers.

並列關鍵字

Perforated corneal ulcers ； Preperforated corneal ulcers ； Tissue adhesives ； Penetrating keratoplasty